Photobiomodulation Therapy as an Adjuvant in Reducing Postoperative Pain in Third Molar Surgery. A Systematic Review
Main Article Content
Abstract
Introduction: Third molar surgery is normally associated with different complications, the main one being postoperative pain. Commonly, therapy focuses on the prescription of nonsteroidal anti-inflammatory drugs (NAIDS) as adjuvants to minimize pain. However, the nsaids have numerous gastrointestinal, renal and haematological side effects. Currently, the implementation of photobiomodulation (PBM) therapy has been suggested, in an effort to offer the best adjuvant treatment in the control of postoperative pain that does not generate side effects. Objective: To make a systematic review on the effectiveness of implementing pbm therapy to reduce postoperative pain in third molar surgery. Materials and methods: A search was performed in three electronic databases: PubMed®, ScienceDirect® and Wiley Online Library. These included randomized controlled trials (RCT) published from 2015 to 2021. Results: A short number of articles were found, none of them had a standardised PBM therapy protocol (wavelength, measured power density, J/cm2 energy per point). Besides, these articles did not present agreement between the characteristics of the PBM therapy application. From the included studies, all showed statistical significance in the reduction of pain when applying PBM therapy. Conclusion: According to the results of this review, the application of pbm therapy is effective in reducing postoperative pain in third molar surgery.
Article Details
Citas en Dimensions Service
References
- Shepherd JP, Brickley M. Surgical removal of third molars. BMJ. 1994; 309: 620. DOI: 10.1136/bmj.309.6955.620
- Lee CT, Zhang S, Leung YY, Li SK, Tsang CC, Chu CH. Patients’ satisfaction and prevalence of complications on surgical extraction of third molar. Patient Prefer Adherence. 2015; 9: 257-263. DOI: 10.2147/PPA.S76236
- Lago-Méndez L, Diniz-Freitas M, Senra-Rivera C, Gude-Sampedro F, Gándara Rey JM, García-García A. Relationships between surgical difficulty and postoperative pain in lower third molar extractions. J Oral Maxillofac Surg. 2007; 65(5): 979-983. DOI: 10.1016/j.joms.2006.06.281
- Bamgbose BO, Akinwande JA, Adeyemo WL, Ladeinde AL, Arotiba GT, Ogunlewe MO. Effects of co-administered dexamethasone and diclofenac potassium on pain, swelling and trismus following third molar surgery. Head Face Med. 2005; 1: 11. DOI: 10.1186/1746-160X-1-11
- Kazancioglu HO, Ezirganli S, Demirtas N. Comparison of the influence of ozone and laser therapies on pain, swelling, and trismus following impacted third-molar surgery. Lasers Med Sci. 2014; 29(4): 1313-1319. DOI: 10.1007/s10103-013-1300-y
- López-Ramírez M, Vílchez-Pérez MA, Gargallo-Albiol J, Arnabat-Domínguez J, Gay-Escoda C. Efficacy of low-level laser therapy in the management of pain, facial swelling, and postoperative trismus after a lower third molar extraction. A preliminary study. Lasers Med Sci. 2012; 27(3): 559-566. DOI: 10.1007/s10103-011-0936-8
- da Silva TMV, Melo TS, de Alencar RC, Pereira JRD, Leão JC, Silva IHM, et al. Photobiomodulation for mucosal repair in patients submitted to dental extraction after head and neck radiation therapy: a double-blind randomized pilot study. Support Care Cancer. 2021; 29(3): 1347-1354. DOI: 10.1007/s00520-020-05608-5
- Alan H, Yolcu Ü, Koparal M, Özgür C, Öztürk SA, Malkoç S. Evaluation of the effects of the low-level laser therapy on swelling, pain, and trismus after removal of impacted lower third molar. Head Face Med. 2016; 12(1): 25. DOI: 10.1186/s13005-016-0121-1
- Bjordal JM, Johnson MI, Iversen V, Aimbire F, Lopes-Martins RAB. Low-level laser therapy in acute pain: a systematic review of possible mechanisms of action and clinical effects in randomized placebo-controlled trials. Photomed Laser Surg. 2006; 24(2): 158-168. DOI: 10.1089/pho.2006.24.158
-Hosseinpour S, Fekrazad R, Arany PR, Ye Q. Molecular impacts of photobiomodulation on bone regeneration: A systematic review. Prog Biophys Mol Biol. 2019; 149: 147-159. DOI: 10.1016/j.pbiomolbio.2019.04.005
- Carroll JD, Milward MR, Cooper PR, Hadis M, Palin WM. Developments in low level light therapy (LLLT) for dentistry. Dent Mater. 2014; 30(5): 465-475. DOI: 10.1016/j.dental.2014.02.006
-de Assis Santos VP, de Oliveira NK, Frare JG, Marques MM, Deboni MCZ. Intraoral versus extraoral single-session photobiomodulation therapy after lower third molar surgery: a pilot study. Laser Dent Sci. 2019; 3(2): 119-127. DOI: 10.1007/s41547-019-00061-y
- Fabre HSC, Navarro RL, Oltramari-Navarro PVP, Oliveira RF, Pires-Oliveira DAA, Andraus RAC, et al. Anti-inflammatory and analgesic effects of low-level laser therapy on the postoperative healing process. J Phys Ther Sci. 2015; 27(6): 1645-1648. DOI: 10.1589/jpts.27.1645
- Eshghpour M, Ahrari F, Takallu M. Is low-level laser therapy effective in the management of pain and swelling after mandibular third molar surgery? J Oral Maxillofac Surg. 2016; 74(7): 1322e1-1322e8. DOI: 10.1016/j.joms.2016.02.030
- Isolan C, Kinalski MD, Leão OAA, Post LK, Isolan TMP, Dos Santos MBF. Photobiomodulation therapy reduces postoperative pain after third molar extractions: A randomized clinical trial. Med Oral Patol Oral Cir Bucal. 2021; 26(3): e341-e348. DOI: 10.4317/medoral.24228
- Mohajerani H, Tabeie F, Alirezaei A, Keyvani G, Bemanali M. Does combined low-level laser and light-emitting diode light irradiation reduce pain, swelling, and trismus after surgical extraction of mandibular third molars? A randomized double-blinded crossover study. J Oral Maxillofac Surg. 2021; 79(8): 1621-1628. DOI: 10.1016/j.joms.2020.07.017
- Momeni E, Barati H, Arbabi MR, Jalali B, Moosavi MS. Low-level laser therapy using laser diode 940 nm in the mandibular impacted third molar surgery: double-blind randomized clinical trial. BMC Oral Health. 2021; 21(1): 77. DOI: 10.1186/s12903-021-01434-1
- Nejat AH, Eshghpour M, Danaeifar N, Abrishami M, Vahdatinia F, Fekrazad R. Effect of photobiomodulation on the incidence of alveolar osteitis and postoperative pain following mandibular third molar surgery: A double-blind randomized clinical trial. Photochem Photobiol. 2021; 97(5): 1129-1135. DOI: 10.1111/php.13457
- Mester E, Mester AF, Mester A. The biomedical effects of laser application. Lasers Surg Med. 1985; 5(1): 31-39. DOI: 10.1002/lsm.1900050105
Xu GZ, Jia J, Jin L, Li JH, Wang ZY, Cao DY. Low-level laser therapy for temporomandibular disorders: A systematic review with meta-analysis. Pain Res Manag. 2018; 2018: 4230583. DOI: 10.1155/2018/4230583
- Munguia FM, Jang J, Salem M, Clark GT, Enciso R. Efficacy of low-level laser therapy in the treatment of temporomandibular myofascial pain: A systematic review and meta-analysis. J Oral Facial Pain Headache. 2018; 32(3): 287-297. DOI: 10.11607/ofph.2032
- Mirzaei A, Saberi-Demneh A, Gutknecht N, Ramezani G. The effect of low-level laser radiation on improving inferior alveolar nerve damage after sagittal split osteotomy: a systematic review. Lasers Med Sci. 2019; 34(5): 865-872. DOI: 10.1007/s10103-019-02718-3
- He M, Zhang B, Shen N, Wu N, Sun J. A systematic review and meta-analysis of the effect of low-level laser therapy (LLLT) on chemotherapy-induced oral mucositis in pediatric and young patients. Eur J Pediatr. 2018; 177(1): 7-17. DOI: 10.1007/s00431-017-3043-4
- Anschau F, Webster J, Capra MEZ, de Azeredo da Silva ALF, Stein AT. Efficacy of low-level laser for treatment of cancer oral mucositis: a systematic review and meta-analysis. Lasers Med Sci. 2019; 34(6): 1053-1062. DOI: 10.1007/s10103-019-02722-7
- Bakdach WMM, Hadad R. Effectiveness of low-level laser therapy in accelerating the orthodontic tooth movement: A systematic review and meta-analysis. Dent Med Probl. 2020; 57(1): 73-94. DOI: 10.17219/dmp/112446
- Deana NF, Zaror C, Sandoval P, Alves N. Effectiveness of low-level laser therapy in reducing orthodontic pain: A systematic review and meta-analysis. Pain Res Manag. 2017; 2017: 8560652. DOI: 10.1155/2017/8560652
- Hosseinpour S, Tunér J, Fekrazad R. Photobiomodulation in oral surgery: A review. Photobiomodul Photomed Laser Surg. 2019; 37(12): 814-825. DOI: 10.1089/photob.2019.4712
- Opel DR, Hagstrom E, Pace AK, Sisto K, Hirano-Ali SA, Desai S, et al. Light-emitting diodes: A brief review and clinical experience. J Clin Aesthet Dermatol. 2015; 8(6): 36-44. PMID: 26155326
- Amarillas-Escobar ED, Toranzo-Fernández JM, Martínez-Rider R, Noyola-Frías MA, Hidalgo-Hurtado JA, Fierro-Serna VM, et al. Use of therapeutic laser after surgical removal of impacted lower third molars. J Oral Maxillofac Surg. 2010; 68(2): 319-324. DOI: 10.1016/j.joms.2009.07.037
- Aras MH, Güngörmüş M. Placebo-controlled randomized clinical trial of the effect two different low-level laser therapies (LLLT)--intraoral and extraoral--on trismus and facial swelling following surgical extraction of the lower third molar. Lasers Med Sci. 2010; 25(5): 641-645. DOI: 10.1007/s10103-009-0684-1

Revista Odontológica Mexicana por Universidad Nacional Autónoma de México se distribuye bajo una Licencia Creative Commons Atribución-NoComercial-SinDerivar 4.0 Internacional.
Basada en una obra en http://revistas.unam.mx/index.php/rom.