Periodontitis Treatment by Scaling and Root Planing with Antimicrobial and Anti-Inflammatory Solutions in a Patient with Systemic Lupus Erythematosus
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Abstract
Introduction: Systemic Lupus Erythematosus is a chronic autoimmune disease of unknown cause in which patients regularly consume immunosuppressants, causing a decrease in body fluids of proteins such as mucins, immunoglobulin A and G antibodies, which causes destruction of periodontal tissue. Objective: To report a clinical case on the benefits of scaling and root planing (srp) with solutions based on hypochlorous acid (HOCl) and modified diallyl disulfide oxide (mddo) in the periodontal inflammatory process in a patient with systemic lupus erythematosus patient, tubulointerstitial nephritis and periodontitis. Case presentation: A 32-year-old woman, with systemic lupus erythematosus, tubulointerstitial nephritis and, according to the 2017 global workshop on the classification of periodontal diseases and conditions, was diagnosed with Stage 2 and Grade B periodontitis. Periodontal assessment revealed a high overall dental plaque index, with high-risk plaque being the most prevalent. srp treatment was carried out by quadrants, applying a HOCl solution during periodontal debridement and periodontal pockets were irrigated with mddo solution to disinfect them. Conclusions: The antimicrobial and anti-inflammatory solutions used as adjuvants to srp in this novel periodontal irrigation therapy helped to reduce gingival inflammation and high-risk plaque, which favoured healing of periodontal tissues in a patient with systemic lupus erythematosus.
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Mok CC, Lau CS. Pathogenesis of systemic lupus erythematosus. J Clin Pathol. 2003; 56(7): 481–490. DOI: 10.1136/jcp.56.7.481
Albandar JM, Susin C, Hughes FJ. Manifestations of systemic diseases and conditions that affect the periodontal attachment apparatus: Case definitions and diagnostic considerations. J Clin Periodontol. 2018; 45(Suppl 20): S171-S189. DOI: 10.1111/jcpe.12947
Lafaurie GI, Calderón JL, Zaror C, Millán LV, Castillo DM. Ácido hipocloroso: una nueva alternativa como agente antimicrobiano y para la proliferación celular para uso en odontología. Int J Odontostomat. 2015; 9(3): 475-481. DOI: 10.4067/S0718-381X2015000300019
Wang L, Bassiri M, Najafi R, Yang J, Khosrovi B, Hwong W, et al. Hypochlorous acid as a potential wound care agent: Part I. Stabilized hypochlorous acid: a component of the inorganic armamentarium of innate immunity. J Burns Wounds. 2007; 6: 65-79. PMID: 17492050
Sam CH, Lu HK. The role of hypochlorous acid as one of the reactive oxygen species in periodontal disease. J Dent Sci. 2009; 4(2): 45-54. DOI: 10.1016/S1991-7902(09)60008-8
Ankri S, Miron T, Rabinkov A, Wilchek M, Mirelman D. Allicin from garlic strongly inhibits proteinases and cytopathic effects of Entamoeba histolytica. Antimicrob Agents Chemother. 1997; 41(10): 2286-2288. DOI: 10.1128/AAC.41.10.2286
Bakri IM, Douglas CW. Inhibitory effect of garlic extract on oral bacteria. Arch Oral Biol. 2005; 50(7): 645- 651. DOI: 10.1016/j.archoralbio.2004.12.002
Borlinghaus J, Albrecht F, Gruhlke MCH, Nwachukwu ID, Slusarenko AJ. Allicin: chemistry and biological properties. Molecules. 2014; 19(8): 12591-12618. DOI: 10.3390/molecules190812591
Mikaili P, Maadirad S, Moloudizargari M, Aghajanshakeri S, Sarahroodi S. Therapeutic uses and pharmacological properties of garlic, shallot, and their biologically active compounds. Iran J Basic Med Sci. 2013; 16(10): 1031-1048. PMID: 24379960
Rabinkov A, Miron T, Konstantinovski L, Wilchek M, Mirelman D, Weiner L. The mode of action of allicin: trapping of radicals and interaction with thiol containing proteins. Biochim Biophys Acta. 1998; 1379(2): 233-244. DOI: 10.1016/s0304-4165(97)00104-9
Sirintawat N, Sawang K, Chaiyasamut T, Wongsirichat N. Pain measurement in oral and maxillofacial surgery. J Dent Anesth Pain Med. 2017; 17(4): 253-263. DOI: 10.17245/jdapm.2017.17.4.253
Hawker GA, Mian S, Kendzerska T, French M. Measures of adult pain: visual analog scale for pain (VAS pain), numeric rating scale for pain (NRS pain), McGill pain questionnaire (MPQ), short-form McGill pain questionnaire (SF-MPQ), chronic pain grade scale (CPGS), short form-36 bodily pain scale (SF-36 BPS), and measure of intermittent and constant osteoarthritis pain (ICOAP). Arthritis Care Res (Hoboken). 2011; 63(Suppl11): S240-S252. DOI: 10.1002/acr.20543
Löe H. The gingival index, the plaque index and the retention index systems. J Periodontol.1967; 38(6): 610–616. DOI: 10.1902/jop.1967.38.6.610
Kulkarni P, Singh DK, Jalaluddin M, Jayanti I. Indices in dentistry: recitation of oral diseases at numerical value. J Res Adv Dent. 2016; 5(2): 261-268. https://www.jrad.co.in/jrad_userfiles/files/46%20Dhirendra%20Kumar%20Singh(1).pdf
Tonetti MS, Greenwell H, Kornman KS. Staging and grading of periodontitis: framework and proposal of a new classification and case definition. J Clin Periodontol. 2018; 45(Suppl20): S149–S161. DOI: 10.1111/jcpe.12945
Saxer UP, Turconi B, Elsässer C. Patient motivation with the papillary bleeding index. J Prev Dent. 1977; 4(4): 20-22. PMID: 351174
Miller SC. Textbook of Periodontia oral medicine. 3 ed. Philadelphia: Blakiston, 1950.
Varadhan KB, Parween S, Bhavsar AK, Prabhuji MLV. Tooth mobility measurements- realities and limitations. J Evolution Med Dent Sci. 2019; 8(16): 1342-1350. DOI: 10.14260/jemds/2019/298
O’Leary TJ, Drake RB, Naylor JE. The plaque control record. J Periodontol. 1972; 43(1): 38. DOI: 10.1902/jop.1972.43.1.38
Doi K, Yoshiga C, Kobatake R, Kawagoe M, Wakamatsu K, Tsuga K. Use of an intraoral scanner to evaluate oral health. J Oral Sci. 2021; 63(3): 292-294. DOI: 10.2334/josnusd.21-0048
Paz García J, Maldonado Rodríguez A, Díaz Reval I, Muñiz J, Rodríguez Hernández A. Sustitución del uso de solución salina fisiológica como irrigante en el manejo de pacientes sépticos y quirúrgicos por solución electrolizada. Rev Mex Cir Bucal Maxilofac. 2011; 7(2): 46-52. https://www.medigraphic.com/pdfs/cirugiabucal/cb-2011/cb112c.pdf
Chen L. The myth of 0.9% saline: neither normal nor physiological. Crit Care Nurs Q. 2015; 38(4): 385-389. DOI: 10.1097/CNQ.0000000000000084
Cobb CM, Sottosanti JS. A re-evaluation of scaling and root planing. J Periodontol. 2021; 92(10): 1370-1378. DOI: 10.1002/JPER.20-0839
Issac AV, Mathew JJ, Ambooken M, Kachappilly AJ, Pk A, Johny T, et al. Management of chronic periodontitis using subgingival irrigation of ozonized water: A clinical and microbiological study. J Clin Diagn Res. 2015; 9(8): ZC29-ZC33. DOI: 10.7860/JCDR/2015/14464.6303
Brunello G, Becker K, Scotti L, Drescher D, Becker J, John G. The effects of three chlorhexidine-based mouthwashes on human osteoblast-like SaOS-2 cells. An in vitro study. Int J Mol Sci. 2021; 22(18): 9986. DOI: 10.3390/ijms22189986
Liu JX, Werner J, Kirsch T, Zuckerman JD, Virk MS. Cytotoxicity evaluation of chlorhexidine gluconate on human fibroblast, myoblasts, and osteoblasts. J Bone Jt Infect. 2018; 3(4): 165-172. DOI:10.7150/jbji.26355
Paul J. Recent trends in irrigation in endodontics. Int J Curr Microbiol App Sci. 2014; 3(11): 941-952. https://www.ijcmas.com/vol-3-11/John%20Paul.pdf
Torres-Capetillo E, Carrillo-Fuentevilla R, De la Garza-Ramos MA, Mercado Hernández R, Torre-Martínez HHH, Segoviano-Ramirez JC. Antimicrobial efficacy of neutral super-oxidized electrolyzed gel versus chlorhexidine digluconate 0.12% in biofilm formation on orthodontic mini-implants: An in vitro study. J Pharmacognosy Phytother. 2013; 5(4): 64-71. DOI:10.5897/JPP12. 063
Tristán López JD, Goldaracena Azuara MP, Ramírez Muñoz CA, González Amaro AM, Ramírez García J. Efecto antimicrobiano de una solución de superoxidación con pH neutro para desinfección de cavidades clase I. Rev ADM. 2015; 72(4): 189-197. https://www.medigraphic.com/pdfs/COMPLETOS/adm/2015/od154.pdf#page=25
Chen CJ, Chen CC, Ding SJ. Effectiveness of hypochlorous acid to reduce the biofilms on titanium alloy surfaces in vitro. Int J Mol Sci. 2016; 17(7): 1161. DOI:10.3390/ijms17071161
Ajay Rao HT, Bhat SS, Hegde S, Jhamb V. Efficacy of garlic extract and chlorhexidine mouthwash in reduction of oral salivary microorganisms, an in vitro study. Anc Sci Life. 2014; 34(2): 85-88. DOI:10.4103/0257-7941.153465
Kudva S, Prabhakar S, Pai V, Tegginamani A. Effects of garlic extract on salivary pH: a clinical study. Arch Orofac Sci. 2012; 7(1): 1-8. https://aos.usm.my/docs/Vol_7/Issue_1/0108.120109.pdf
Eswar K, Venkateshbabu N, Rajeswari K, Kandaswamy D. Dentinal tubule disinfection with 2% chlorhexidine, garlic extract, and calcium hydroxide against Enterococcus faecalis by using real-time polymerase chain reaction: In vitro study. J Conserv Dent. 2013; 16(3): 194-198. DOI:10.4103/0972-0707.111312 https://journals.lww.com/jcde/fulltext/2013/16030/dentinal_tubule_disinfection_with_2_.2.aspx
Lee HJ, Park HS, Kim KH, Kwon TY, Hong SH. Effect of garlic on bacterial biofilm formation on orthodontic wire. Angle Orthod. 2011; 81(5): 895-900. DOI:10.2319/121010-713.
Khan L, Miranda Paulino EG, Lim D, Nadela F, Yadav R, Singh Birring OJ. Anti-microbial efficacy of Allium sativum against Streptococcus mutans biofilm formation on orthodontic mini-implants. J Orthod Res. 2014; 2(3): 129-134. DOI:10.4103/2321-3825.140683
Lafaurie GI, Aya MR, Arboleda S, Escalante A, Castillo DM, Millán LV, et al. Eficacia desinfectante del ácido hipocloroso sobre cepas con poder patogénico de cavidad oral. Rev Colomb Investig Odontol. 2009; 1(1): 3-11.
Armstrong D, Bohn G, Glat P, Kavros SJ, Kirsner R, Snyder R, et al. Expert recommendations for the use of hypochlorous solution: science and clinical application. Ostomy Wound Manage. 2015; 61(5): S2-S19. PMID: 28692424
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