Factores de riesgo modificables en las mujeres embarazadas para el desarrollo de trastornos mentales: revisión integrativa

Contenido principal del artículo

Lina Marcela Balanta Gonzaliaz
Leydi Victoria Omedo
Jorsy Andres Ocoro Vergara
Olga Lucía Gaitán-Gómez

Resumen

Introducción: un estudio desarrollado en Australia reporta que un 20% de las embarazadas padecen trastornos mentales durante el embarazo, de las cuales hasta un 85% no reciba atención médica focalizada, también, se ha reportado que menos del 20% del personal de atención primaria en salud lleva a cabo alguna evaluación para identificar riesgos en salud mental. Objetivo: analizar los hallazgos científicos sobre los factores de riesgo modificables de la mujer embarazada para el desarrollo de trastornos mentales. Metodología: revisión integradora de la literatura en seis bases de datos, realizada entre agosto y noviembre del año 2021. Se siguieron las directrices PRISMA que permitieron la identificación 36 cumplieron con la pregunta clínica PICOT y los criterios de inclusión. Resultados y discusión: los factores de riesgo modificables más reportados en la literatura fueron los relacionados con el estilo de vida, el acceso a los servicios de salud y la preocupación excesiva por situaciones socioeconómicas-familiares, siendo en conjunto desencadenante de inestabilidad emocional y estrés, y ser terreno fértil para el desarrollo de trastornos mentales durante la gestación. Del mismo modo, se propone un plan de atención de enfermería enfocado en las respuestas y necesidades humanas identificadas en el estudio. Conclusiones: el estudio identifica los factores de riesgo modificable más reportados en la literatura para su reconocimiento e inclusión en los programas de atención integral prenatal, retroalimentación de las teorías y modelos en enfermería, reorientar los procesos formativos y la transformación de las políticas públicas en salud a procesos vitales y no a patologías.

Descargas

Los datos de descargas todavía no están disponibles.

Detalles del artículo

Cómo citar
Balanta Gonzaliaz, L. M., Victoria Omedo, L., Ocoro Vergara, J. A., & Gaitán-Gómez, O. L. (2023). Factores de riesgo modificables en las mujeres embarazadas para el desarrollo de trastornos mentales: revisión integrativa. Revista CuidArte, 12(23). https://doi.org/10.22201/fesi.23958979e.2023.12.23.84887
Biografía del autor/a

Lina Marcela Balanta Gonzaliaz

Enfermera profesional, Hospital Universitario del Valle “Evaristo García”, Santiago de Cali, Colombia.

Leydi Victoria Omedo

Estudiante de enfermería, Universidad Santiago de Cali, Colombia.

Jorsy Andres Ocoro Vergara

Enfermero, Universidad Santiago de Cali, Colombia.

Olga Lucía Gaitán-Gómez

Enfermera, Doctora en enfermería, docente de tiempo completo del programa de enfermería, Universidad Nacional de Colombia, Universidad de Santiago de Cali, Colombia.

Citas

(1). Mojica-Perilla M, Parra-Villa Y, Osma Zambrano SE. Tamización de síntomas de depresión, ansiedad prenatal y factores de riesgo psicosocial asociados en usuarias del servicio de control prenatal. Reflexiones en torno a la construcción del protocolo. MedUNAB [Internet] 2019 [citado el 2 Mar 2022];22(3):341–55. DOI: 10.29375/01237047.2867

(2). Kingston D, Austin MP, Hegadoren K, McDonald S, Lasiuk G, McDonald S, et al. Study protocol for a randomized, controlled, superiority trial comparing the clinical and cost- effectiveness of integrated online mental health assessment-referral-care in pregnancy to usual prenatal care on prenatal and postnatal mental health and infant health and development: The Integrated Maternal Psychosocial Assessment to Care Trial (IMPACT). Trials. BioMed Central Ltd. [Internet] 2014 [citado el 2 Mar 2022];15(1). DOI: 10.1186/1745-6215-15-72

(3). Atif N, Lovell K, Rahman A. Maternal mental health: The missing “m” in the global maternal and child health agenda. Semin Perinatol. Semin Perinatol [Internet] 2015 [citado el 2 Mar 2022];39(5):345–52. DOI: 10.1053/j.semperi.2015.06.007

(4). García A. Una de cada 5 mujeres sufre problemas de salud mental durante la maternidad: “Si no se trata, se puede cronificar.” Nius Diario. Barcelona [Revista en Internet] 2021 [citado el 26 Feb 2022]; Disponible: https://bit.ly/3H3JLub

(5). Pérez D, Rodríguez M, Rodríguez A. Prevalencia de trastorno mental en embarazadas. Arch méd Camagüey [Internet]. 2020 [citado el 26 Feb 2022];24(4):503–11. Disponible: https://bit.ly/3sqzx31

(6). Flores-Ramos M. La salud mental en la mujer embarazada, Perinatología y reproducción humana. Perinatol Reprod Hum [Internet]. 2013 [citado el 26 Feb 2022];27(3):143–4. Disponible: https://bit.ly/3M834Gz

(7). Osma-Zambrano SE, Lozano-Osma MD, Mojica-Perilla M, Redondo-Rodríguez S. Prevalencia de depresión y ansiedad y variables asociadas en gestantes de Bucaramanga y Floridablanca (Santander, Colombia). MedUNAB [Internet] 2019 [citado el 2 Mar 2022];22(2):171–85. DOI: https://doi.org/10.29375/01237047.3586

(8). Guimaraes F, da Silva F, Ben A, Rolim V, de Sousa G, Albuquerque J. Enfermedad mental en mujeres embarazadas. Enfermeria Global [Internet] 2019 [citado el 26 Feb 2022];18(53):499–510. DOI: https://doi.org/10.6018/eglobal.18.1.328331

(9). RC Psych [Internet]. Royal College of Pyschiatrists. Mental Health in Pregnancy; 2021 [citado el 26 Feb 2022]. Disponible: https://bit.ly/34TACYg

(10). Austin M, Highet. Clinical practice guidelines for depression and related disorders – anxiety, bipolar disorder and puerperal psychosis – in the perinatal period. A guideline for primary care health professionals - Resources - Promote and practice - Australian Indigenous HealthInfoNet. Guidelines Expert Advisory Committee [Internet]. 2011 [citado el 2 Mar 2022]; Disponible: https://bit.ly/3vyn4fK

(11). Austin MP. Clinical Practice Guidelines. Depression and related disorders-anxiety, bipolar disorder and puerperal psychosis-in the perinatal period [Internet]. Beyondblue. Australia; 2011. Disponible: https://bit.ly/3IHWAfo

(12). Biaggi A, Conroy S, Pawlby S, Pariante CM. Identifying the women at risk of antenatal anxiety and depression: A systematic review. J Affect Disord [Internet] 2016 [citado el 2 Mar 2022];191:62–77. Disponible: https://bit.ly/3pBWfn3. DOI: 10.1016/j.jad.2015.11.014

(13). Martínez J, Jácome N. Depresión en el embarazo. Revista colombiana de psiquiatría [Internet]. 2019 [citado el 2 Mar 2022];48(1):58–65. DOI: https://doi.org/10.1016/j.rcp.2017.07.003

(14). Serpeloni F, Radtke K, de Assis SG, Henning F, Nätt D, Elbert T. Grandmaternal stress during pregnancy and DNA methylation of the third generation: an epigenome-wide association study. Translational Psychiatry 2017 7:8. Nature Publishing Group [Internet] 2017 [citado el 30 Mar 2022];7(8):e1202–e1202. DOI: https://doi.org/10.1038/tp.2017.153

(15). Viuff AC, Sharp GC, Rai D, Henriksen TB, Pedersen LH, Kyng KJ, et al. Maternal depression during pregnancy and cord blood DNA methylation: findings from the Avon Longitudinal Study of Parents and Children. Translational Psychiatry 2018 8:1. Nature Publishing Group [Internet] 2018 [citado el 30 Mar 2022];8(1):1–10. DOI: https://doi.org/10.1038/s41398-018-0286-4

(16). Maldonado M, Sauceda J, Lartigue T. Cambios fisiológicos y emocionales durante el embarazo normal y la conducta del feto. Perinatal Reprod Hum [Internet]. 2008 [citado el 30 Mar 2022];22(1):5–14. Disponible: https://bit.ly/38jN70D

(17). Bermejo J. Miedos más comunes durante el embarazo y cómo enfrentarlos. Ser Padres [Internet] 2021 [citado el 30 Mar 2022]. Disponible: https://bit.ly/3NDnbgz

(18). Mansell T, Novakovic B, Meyer B, Rzehak P, Vuillermin P, Ponsonby AL, et al. The effects of maternal anxiety during pregnancy on IGF2/H19 methylation in cord blood. Translational Psychiatry 2016 6:3. Nature Publishing Group [Internet] 2016 [citado el 30 Mar 2022];6(3):e765–e765. DOI: https://doi.org/10.1038/tp.2016.32

(19). Martín Maldonado-Durán. Salud Mental Perinatal. [Interent] Washington: Organización Panamericana de la Salud; 2011. Disponible: https://bit.ly/35vZ8yz

(20). Wilcox M, McGee BA, Ionescu DF, Leonte M, LaCross L, Reps J, et al. Perinatal depressive symptoms often start in the prenatal rather than postpartum period: results from a longitudinal study. Arch Womens Ment Health. Arch Womens Ment Health [Internet] 2021 [citado el 26 Feb 2022];24(1):119–31. DOI: 10.1007/s00737-020-01017-z

(21). O’Connor E, Rossom RC, Henninger M, Groom HC, Burda BU. Primary Care Screening for and Treatment of Depression in Pregnant and Postpartum Women: Evidence Report and Systematic Review for the US Preventive Services Task Force. JAMA [Internet] 2016 [citado el 2 Mar 2022];315(4):388–406. DOI: 10.1001/jama.2015.18948

(22). Roncallo C, Sánchez M, Arranz E. Maternal-foetal bonding: implications for psychological development and proposal for early intervention. Escritos de Psicologia [Internet] 2015 [citado el 26 Feb 2022];8(2):14–23. DOI: 10.5231/psy.writ.2015.0706

(23). OMS [Internet]. Organización Mundial de la Salud. La OMS señala que las embarazadas deben poder tener acceso a una atención adecuada en el momento adecuado; 2016 [citado el 26 Feb 2022]. Disponible: https://bit.ly/3H8h6Et

(24). Marín D, Bullones Á, Carmona F, Carretero I, Moreno A, Peñacoba C. Influencia de los factores psicológicos en el embarazo, parto y puerperio. Un estudio longitudinal. NURE Investigación. [Internet] 2008 [citado el 2 Mar 2022];37:1–30. Disponible: https://bit.ly/3pA5cNU

(25). Fernanda G, Bellotti J. Tratamiento Psiquiátrico en el embarazo y lactancia. Su estigma socioambiental. Psiquiatria [Internet] 2020 [citado el 30 Mar 2022];1(1):1–10. Disponible: https://bit.ly/3Dv66kh

(26). Page MJ, Mckenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ [Internet] 2021 [citado el 26 Feb 2022];372(71):1–9. DOI: http://dx.doi.org/10.1136/bmj.n71

(27). Rodríguez A. Bases de datos e índices de revistas científicas. Fundación iS+D [Internet] 2019 [citado el 26 Feb 2022]. Disponible: https://bit.ly/3C6tW5m

(28). Universidad de los Andes. Guía para la revisión y el reporte de literatura científica [Internet]. 2018. Disponible: https://bit.ly/3vBG6BJ

(29). Bardin L. Análisis de contenido. 3rd ed. [Internet] España: Ediciones Akal; 2002 [citado el 17 Mar 2022]. Disponible: https://bit.ly/3N4oqFe

(30). Okun ML, Kiewra K, Luther JF, Wisniewski SR, Wisner KL. Sleep Disturbances in Depressed and Non-Depressed Pregnant Women. Depress Anxiety [Internet] 2011 [citado el 26 Feb 2022];28(8):676–85. Disponible: https://bit.ly/3IuFuS2. DOI:10.1002/da.20828.

(31). Akgor U, Fadıloglu E, Burcu S, Canan U, Murat C, Temiz E, et al. Anxiety, depression and concerns of pregnant women during the COVID-19 pandemic. Archives of Gynecology and Obstetrics [Internet] 2021 [citado el 26 Feb 2022];304:125–30. DOI: https://doi.org/10.1007/s00404-020-05944-1

(32). Oskovi-Kaplan ZA, Buyuk GN, Ozgu-Erdinc AS, Keskin HL, Ozbas A, Moraloglu Tekin O. The Effect of COVID-19 Pandemic and Social Restrictions on Depression Rates and Maternal Attachment in Immediate Postpartum Women: a Preliminary Study. Psychiatric Quarterly. Springer [Internet] 2021 [citado el 26 Feb 2022];92(2):675–82. DOI: https://doi.org/10.1007/s11126-020-09843-1

(33). Fellmeth G, Plugge E, Paw KM, Charunwatthana P, Nosten F, McGready R. Pregnant migrant and refugee women’s perceptions of mental illness on the Thai-Myanmar border: a qualitative study. BMC Pregnancy and Childbirth. BioMed Central Ltd. [Internet] 2015 [citado el 26 Feb 2022];15(1):1–11. DOI: https://doi.org/10.1186/s12884-015-0517-0

(34). Liu S, Yan Y, Gao X, Xiang S, Sha T, Zeng G, et al. Risk factors for postpartum depression among Chinese women: Path model analysis. BMC Pregnancy and Childbirth. BioMed Central Ltd. [Internet] 2017 [citado el 26 Feb 2022];17(1):1–7. DOI: https://doi.org/10.1186/s12884-017-1320-x

(35). Garman EC, Schneider M, Lund C. Perinatal depressive symptoms among low-income South African women at risk of depression: Trajectories and predictors. BMC Pregnancy and Childbirth. BioMed Central Ltd. [Internet] 2019 [citado el 26 Feb 2022];19(1):1–11. DOI: https://doi.org/10.1186/s12884-019-2355-y

(36). Ni Q, Cheng G, Chen A, Heinonen S. Early detection of mental illness for women suffering high-risk pregnancies: An explorative study on self-perceived burden during pregnancy and early postpartum depressive symptoms among Chinese women hospitalized with threatened preterm labour. BMC Psychiatry. BioMed Central Ltd. [Internet] 2020 [citado el 26 Feb 2022];20(1):1–11. DOI: https://doi.org/10.1186/s12888-020-02667-0

(37). Duko B, Ayano G, Bedaso A. Depression among pregnant women and associated factors in Hawassa city, Ethiopia: an institution-based cross-sectional study. Reprod Health [Internet] 2019 [citado el 26 Feb 2022];16(1):1–6. DOI: https://doi.org/10.1186/s12978-019-0685-x

(38). Lilliecreutz C, Josefsson A, Mohammed H, Josefsson A, Sydsjö G. Mental disorders and risk factors among pregnant women with depressive symptoms in Sweden-A case-control study. Acta Obstet Gynecol Scand. Acta Obstet Gynecol Scand [Internet] 2021 [citado el 26 Feb 2022];100(6):1068–74. DOI: 10.1111/aogs.14051

(39). Ceulemans M, Foulon V, Ngo E, Panchaud A, Winterfeld U, Pomar L, et al. Mental health status of pregnant and breastfeeding women during the COVID-19 pandemic-A multinational cross-sectional study. Acta Obstet Gynecol Scand [Internet] 2021 [citado el 26 Feb 2022];100(7):1219–29. DOI: 10.1111/aogs.14092

(40). Yu Y, Zhu X, Xu H, Hu Z, Zhou W, Zheng B, et al. Prevalence of depression symptoms and its influencing factors among pregnant women in late pregnancy in urban areas of Hengyang City, Hunan Province, China: a cross-sectional study. BMJ Open [Internet] 2020 [citado el 26 Feb 2022];10(9). DOI: 10.1136/bmjopen-2020-038511

(41). Hartmann JM, Mendoza-Sassi RA, Cesar JA. Depressão entre puérperas: prevalência e fatores associados. Cadernos de Saúde Pública. Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz [Internet] 2017 [citado el 26 Feb 2022];33(9):1–10. DOI:10.1590/0102-311X00094016

(42). Johnson A, George M, Goud BR, Sulekha T. Screening for Mental Health Disorders among Pregnant Women Availing Antenatal Care at a Government Maternity Hospital in Bengaluru City. Indian J Psychol Med [Internet] 2018 [citado el 26 Feb 2022];40(4):343–8. DOI: 10.4103/IJPSYM.IJPSYM_41_18

(43). Belete K, Kassew T, Demilew D, Zeleke TA. Prevalence and Correlates of Suicide Ideation and Attempt among Pregnant Women Attending Antenatal Care Services at Public Hospitals in Southern Ethiopia. Neuropsychiatr Dis Treat [Internet] 2021 [citado el 26 Feb 2022];17:1517–29. DOI: 10.2147/NDT.S309702

(44). Barcelona de Mendoza V, Harville EW, Savage J, Giarratano G. Experiences of intimate partner and neighborhood violence and their association with mental health in pregnant women. J Interpers Violence. NIH Public Access [Internet] 2018 [citado el 26 Feb 2022];33(6):959. DOI: 10.1177/0886260515613346

(45). D’Anna-Hernandez KL, García E, Coussons-Read M, Laudenslager ML, Ross RG. Sleep Moderates and Mediates the Relationship Between Acculturation and Depressive Symptoms in Pregnant Mexican-American Women. Matern Child Health J [Internet] 2016 [citado el 26 Feb 2022];20(2):422–33. DOI: 10.1007/s10995-015-1840-9

(46). Sánchez SE, Pineda O, Chaves DZ, Zhong QY, Gelaye B, Simon GE, et al. Childhood Physical and Sexual Abuse Experiences Associated with Post Traumatic Stress Disorder among Pregnant Women. Ann Epidemiol. NIH Public Access [Internet] 2017 [citado el 26 Feb 2022];27(11):716. DOI: 10.1016/j.annepidem.2017.09.012

(47). Palfreyman A. Addressing Psychosocial Vulnerabilities Through Antenatal Care-Depression, Suicidal Ideation, and Behavior: A Study Among Urban Sri Lankan Women. Front Psychiatry. Front Psychiatry [Internet] 2021 [citado el 26 Feb 2022];12:1–14. DOI: 10.3389/fpsyt.2021.554808

(48). Lee H, Kim KE, Kim MY, Park CG. Cluster Analysis of the Combined Association of Sleep and Physical Activity with Healthy Behavior and Psychological Health in Pregnant Women. Int J Environ Res Public Health [Internet] 2021 [citado el 26 Feb 2022];18(4):1–11. DOI: 10.3390/ijerph18042185

(49). Harron K, Gilbert R, Fagg J, Guttmann A, van der Meulen J. Associations between pre-pregnancy psychosocial risk factors and infant outcomes: a population-based cohort study in England. The Lancet Public Health. Elsevier Ltd. [Internet] 2021 [citado el 26 Feb 2022];6(2):97–105. DOI: https://doi.org/10.1016/S2468-2667(20)30210-3

(50). Cena L, Mirabella F, Palumbo G, Gigantesco A, Trainini A, Stefana A. Prevalence of maternal antenatal and postnatal depression and their association with sociodemographic and socioeconomic factors: A multicentre study in Italy. J Affect Disord [Internet] 2021 [citado el 26 Feb 2022];279:217–21. DOI: 10.1016/j.jad.2020.09.136

(51). Liu J, Hung P, Alberg AJ, Hair NL, Whitaker KM, Simon J, et al. Mental health among pregnant women with COVID-19-related stressors and worries in the United States. Birth [Internet] 2021 [citado el 26 Feb 2022];48(4):470–9. DOI: 10.1111/birt.12554

(52). Faisal-Cury A, Caires Rocha A, Machado Ribeiro Silotto A, Oliveira Rodrigues D. Prevalence and associated risk factors of antenatal depression among Brazilian pregnant women: A population-based study. Journal of Affective Disorders Reports. Elsevier [Internet] 2021 [citado el 26 Feb 2022];5:100166. DOI: https://doi.org/10.1016/j.jadr.2021.100166

(53). Bright KS, Wajid A, McNeil DA, Stuart S, Kingston D. Profiles of women participating in an internet-based prenatal mental health platform (HOPE – Healthy Outcomes of Prenatal and Postnatal Experiences). Journal of Affective Disorders Reports. Elsevier BV [Internet] 2021 [citado el 26 Feb 2022];4:100135. DOI: 10.1016/j.jadr.2021.100135

(54). Wang WJ, Hou CL, Jiang YP, Han F zhen, Wang XY, Wang S bin, et al. Prevalence and associated risk factors of insomnia among pregnant women in China. Comprehensive Psychiatry. W.B. Saunders [Internet] 2020 [citado el 26 Feb 2022];98:152168. DOI: https://doi.org/10.1016/j.comppsych.2020.152168

(55). Mwita M, Kasongi D, Bernard E, Gunda D, Mmbaga B. The magnitude and determinants of antepartum depression among women attending antenatal clinic at a tertiary hospital, in Mwanza Tanzania: a cross-sectional study. Pan Afr Med J [Internet] 2021 [citado el 26 Feb 2022];38(258):1–9. DOI: 10.11604/pamj.2021.38.258.27023

(56). Masters GA, Brenckle L, Sankaran P, Person SD, Allison J, Moore Simas TA, et al. Positive screening rates for bipolar disorder in pregnant and postpartum women and associated risk factors. Gen Hosp Psychiatry [Internet] 2019 [citado el 26 Feb 2022];61:53–9. DOI: 10.1016/j.genhosppsych.2019.09.002

(57). Parcesepe AM, Cordoba E, Gallis JA, Headley J, Tchatchou B, Hembling J, et al. Common mental disorders and intimate partner violence against pregnant women living with HIV in Cameroon: a cross-sectional analysis. BMC Pregnancy and Childbirth. BioMed Central Ltd [Internet] 2021 [citado el 26 Feb 2022];21(1):1–14. DOI: https://doi.org/10.1186/s12884-021-03673-0

(58). Ola B, Crabb J, Tayo A, Gleadow Ware SH, Dhar A, Krishnadas R. Factors associated with antenatal mental disorder in West Africa: A cross-sectional survey. BMC Pregnancy and Childbirth. BioMed Central [Internet] 2011 [citado el 26 Feb 2022];11(1):1–6. DOI: https://doi.org/10.1186/1471-2393-11-90

(59). Uguz F, Yakut E, Aydogan S, Bayman MG, Gezginc K. Prevalence of mood and anxiety disorders during pregnancy: A case-control study with a large sample size. Psychiatry Res [Internet] 2019 [citado el 26 Feb 2022];272:316–8. DOI: 10.1016/j.psychres.2018.12.129

(60). Andersson L, Sundström-Poromaa I, Wulff M, Åström M, Bixo M. Depression and anxiety during pregnancy and six months postpartum: a follow-up study. Acta Obstet Gynecol Scand [Internet] 2006 [citado el 26 Feb 2022];85(8):937–44. DOI: 10.1080/00016340600697652

(61). Adewuya A, Ola B, Aloba O, Moyosore B. Anxiety disorders among Nigerian women in late pregnancy: A controlled study. Archives of Women’s Mental Health [Internet] 2006 [citado el 26 Feb 2022];9(6):325–8. DOI: 10.1007/s00737-006-0157-5

(62). Borda M, Forero C, Ahcar N, Hinestrosa C, Polo S, Staaden M, et al. Depresión y factores de riesgos asociados en embarazadas de 18 a 45 años asistentes al Hospital Niño de Jesús en Barranquilla (Colombia). Salud Uninorte [Internet] 2013 [citado el 26 Feb 2022];29(3):394–405. Disponible: https://bit.ly/3thDQwX

(63). van Heyningen T, Honikman S, Myer L, Onah MN, Field S, Tomlinson M. Prevalence and predictors of anxiety disorders amongst low-income pregnant women in urban South Africa: a cross-sectional study. Arch Womens Ment Health [Internet] 2017 [citado el 26 Feb 2022];20(6):765–75. DOI: 10.1007/s00737-017-0768-z

(64). Artal R. Factores de riesgo para el embarazo de alto riesgo. Manual MSD versión para público general [Internet] 2020 [citado el 26 Feb 2022]. Disponible: https://msdmnls.co/3hq1t0C

(65). Carvajal J, Ralph C. Manual de Obstetricia y Ginecología. 8th ed. [Internet] Pontificia Universidad Católica de Chile; 2017 [citado el 26 Feb 2022]. p. 622. Disponible: https://bit.ly/3smXMPD

(66). Kornfield SL, Riis VM, McCarthy C, Elovitz MA, Burris HH. Maternal perceived stress and the increased risk of preterm birth in a majority non-Hispanic Black pregnancy cohort. Journal of Perinatology. Nature Publishing Group [Internet] 2021 [citado el 3 Apr 2022];1(1):1–6. DOI: 10.1038/s41372-021-01186-4

(67). Sammallahti S, Cortes Hidalgo AP, Tuominen S, Malmberg A, Mulder RH, Brunst KJ, et al. Maternal anxiety during pregnancy and newborn epigenome-wide DNA methylation. Molecular Psychiatry. Nature Publishing Group [Internet] 2021 [citado el 3 Apr 2022];26(6):1832–45. DOI: 10.1038/s41380-020-00976-0

(68). van der CJ, Shitrit ABG. Pregnancy, psychiatry and IBD: multidisciplinary care is crucial. Nature Reviews Gastroenterology & Hepatology. Nature Publishing Group [Internet] 2019 [citado el 3 Apr 2022];16(5):265–6. DOI: 10.1038/s41575-019-0135-9

(69). Woldetsadik AM, Ayele AN, Roba AE, Haile GF, Mubashir K. Prevalence of common mental disorder and associated factors among pregnant women in South-East Ethiopia, 2017: a community based cross-sectional study. Reproductive Health. BioMed Central Ltd. [Internet] 2019 [citado el 3 Apr 2022];16(1):1–8. DOI:1186/s12978-019-0834-2

(70). Guler O, Sahin FK, Emul HM, Ozbulut O, Gecici O, Uguz F, et al. The prevalence of panic disorder in pregnant women during the third trimester of pregnancy. Compr Psychiatry [Internet] 2008 [citado el 26 Feb 2022];49(2):154–8. DOI: 10.1016/j.comppsych.2007.08.008

(71). Cattane N, Räikkönen K, Anniverno R, Mencacci C, Riva MA, Pariante CM, et al. Depression, obesity and their comorbidity during pregnancy: effects on the offspring’s mental and physical health. Molecular Psychiatry. Nature Publishing Group [Internet] 2020 [citado el 3 Apr 2022];26(2):462–81. DOI: 10.1038/s41380-020-0813-6

(72). Friedman LE, Aponte C, Perez Hernandez R, Velez JC, Gelaye B, Sánchez SE, et al. Migraine and the risk of post-traumatic stress disorder among a cohort of pregnant women. J Headache Pain [Internet] 2017 [citado el 3 Apr 2022];18(1). DOI: 10.1186/s10194-017-0775-5

(73). Jami ES, Hammerschlag AR, Bartels M, Middeldorp CM. Parental characteristics and offspring mental health and related outcomes: a systematic review of genetically informative literature. Translational Psychiatry. Nature Publishing Group [Internet] 2021 [citado el 3 Apr 2022];11(1):1–38. Disponible: DOI: https://doi.org/10.1038/s41398-021-01300-2

(74). Zhang X, Suo X, Yang X, Lai H, Pan N, He M, et al. Structural and functional deficits and couplings in the cortico-striato-thalamo-cerebellar circuitry in social anxiety disorder. Translational Psychiatry. Nature Publishing Group [Internet] 2022 [citado el 3 Apr 2022];12(1):1–11. Disponible: DOI: https://doi.org/10.1038/s41398-022-01791-7

(75). Alonso A. Trastornos psicológicos más comunes durante el embarazo. Psyciencia [Internet] 2015 [citado el 26 Feb 2022]. Disponible: https://bit.ly/3p1Ywru

(76). Carrillo P, Barajas K, Sánchez I, Rangel M. Trastornos del sueño: ¿Qué son y cuáles son sus consecuencias? Revista de la Facultad de Medicina de la UNAM [Internet] 2017 [citado el 26 Feb 2022];61(1):6–20. Disponible: https://bit.ly/3C1EuCO

(77). Langan R, Goodbred A. Identification and Management of Peripartum Depression - American Family Physician. Am Fam Physician [Internet] 2016 [citado el 4 Apr 2022];93(10):852–8. Disponible: https://bit.ly/3j98uE5. PMID: 27175720

(78). Vadini F, Tracanna E, Polilli E, Tontodonati M, Ricci E, Santilli F, et al. Post-traumatic stress in pregnant women with primary cytomegalovirus infection and risk of congenital infection in newborns. BJPsych Open. Royal College of Psychiatrists [Internet] 2016 [citado el 4 Apr 2022];2(6):376. DOI: 10.1192/bjpo.bp.116.003152

(79). Salehi L, Rahimzadeh M, Molaei E, Zaheri H, Esmaelzadeh-Saeieh S. The relationship among fear and anxiety of COVID-19, pregnancy experience, and mental health disorder in pregnant women: A structural equation model. Brain and Behavior. John Wiley & Sons, Ltd. [Internet] 2020 [citado el 4 Apr 2022];10(11):e01835. DOI: https://doi.org/10.1002/brb3.1835