Association Between Treatments in Breast Cancer Patients with Clinical and Molecular Classification

Abstract

Objective: to determine the types of treatments in patients with breast cancer according to a clinical and molecular classification, in a Family Medicine Unit. Methods: a cross sectional study based on the review of 88 files that met the requirements of the selection criteria. A data collection format was designed to know the year breast cancer was diagnosed, type of treatment, tnm classification, and molecular profile. The results are shown in frequencies, mean and standard deviation. Results: the average age was 54.5 (±11.4 years), most of the detected cancer types were luminal B with 52% of cases, which were mainly associated to adjuvant chemotherapy (P=0.0001), while triple negative ones were associated to radical surgery (P=0.002). On the other hand, the patients who required the most neoadjuvant, adjuvant and surgical treatment were in stage I at the time of diagnosis, P=0.004, P=0.028 and P=0.007, respectively. Conclusions: correlating treatment types with molecular and tnm classification, it was observed that a significant fraction of patients with luminal B breast cancer required adjuvant chemotherapy and radical surgery, while most triple negative patients required radical surgery.