Factors Associated to the Decrease of Glomerular Filtration in Patients with Diabetes Mellitus Type 2

Abstract

Objective: to determine the factors associated to the decrease of glomerular filtration in patients with diabetes mellitus type 2. Methods: observational, case analytical and control study in patients with diabetes mellitus type 2 diagnostic. Data was gathered based on the glomerular filtration rate (controls: 1-2, cases: 3-5), 151 patients per group. Risk factors associated to the decrease of glomerular filtration were determined. The statistical analysis was made according to measures of central trend, odds ratio, confidence intervals and χ2. Results: the mean age was 52 ± 6.4 years, the associated factors to the glomerular filtration decrease were: polypharmacy (or: 1.662), comorbidities (or: 1.796), poor therapeutic adherence (or: 1.883), poor glycemic control (or: 2.224), low educational level (or: 3.05), poverty (or: 1.34). As protective factors: integrated family typology (or: 0.643), and comply with family basic functions (or: 0.629). Conclusion: the polypharmacy, comorbidities, bad therapeutic adhesion and bad glycemic control are factors strongly associated to the decrease of the glomerular filtration.